发明名称 SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS
摘要 <p>The present invention provides compounds of the general formula wherein R<SUP>4 </SUP>is one of the following groups and R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, and R<SUP>9 </SUP>are as defined in the specification and pharmaceutically acceptable salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. The compounds are useful for the treatment of Alzheimer's disease.</p>
申请公布号 EP1673347(B1) 申请公布日期 2015.08.19
申请号 EP20040787028 申请日期 2004.09.27
申请人 F. HOFFMANN-LA ROCHE AG 发明人 FLOHR, ALEXANDER;GALLEY, GUIDO;JAKOB-ROETNE, ROLAND;KITAS, ERIC, ARGIRIOS;PETERS, JENS-UWE;WOSTL, WOLFGANG
分类号 C07D223/18;A61K31/55;A61K31/5513;A61P25/28;C07D223/16;C07D243/12;C07D243/24;C07D409/12 主分类号 C07D223/18
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