发明名称 Formulation
摘要 The present invention relates to therapeutic formulations based on pumpkin products, in particular to encapsulated formulations for oral administration. A product of the invention comprises a hard gelatin capsule which encloses a unit dose of a formulation which comprises at least 50% by weight of one or more pumpkin product.
申请公布号 US9107846(B2) 申请公布日期 2015.08.18
申请号 US200812666609 申请日期 2008.07.02
申请人 Omega Pharma Innovation and Development NV 发明人 Rustenbeck Peter;Schmid Martina;Theurer Christoph;Wurtz Stephan
分类号 A61K36/42;A61K9/48;A61K36/185;A61K36/22;A61K36/48 主分类号 A61K36/42
代理机构 Crowell & Moring LLP 代理人 Crowell & Moring LLP
主权项 1. A process for the production of a hard gelatin capsule encapsulating a formulation comprising at least 50% by weight of a pumpkin product comprising pumpkin seed oil and particulate pumpkin seed matter wherein the process comprises the steps of: providing a liquid formulation comprising pumpkin seed oil and particulate pumpkin seed matter in a vessel; agitating the liquid formulation so as to maintain the particulate pumpkin seed matter therein in suspension; feeding the formulation into a capsule filling station via a filling flow line; introducing a unit dose volume of the liquid formulation into a hard gelatin part capsule via the filling station whereby prior to introducing the formulation into the hard gelatin part capsule, wherein the particle size of the pumpkin seed matter is reduced to a particle size of less than 300 microns; and closing the hard gelatin part capsule to form a closed capsule after introduction of the formulation into the hard gelatin part capsule.
地址 Nazareth BE