发明名称 |
NOVEL AGONISTS OF TOLL-LIKE RECEPTOR 3 AND METHODS OF THEIR USE |
摘要 |
<p>TLR3 agonist compounds, compositions and methods are provided for stimulating the activity of TLR3. The compositions comprise oligonucleotide-based compounds that bind to and activate TLR3. The compositions may also comprise oligonucleotide-based compounds that bind to and activate TLR3 in combination with other therapeutic and/or prophylactic compounds and/or compositions. Methods of using these compounds and compositions for stimulation of TLR3 activity and for prevention or treatment of diseases wherein modulation of TLR3 activity would be beneficial are provided.</p> |
申请公布号 |
CA2802721(C) |
申请公布日期 |
2015.08.18 |
申请号 |
CA20112802721 |
申请日期 |
2011.06.24 |
申请人 |
IDERA PHARMACEUTICALS, INC. |
发明人 |
KANDIMALLA, EKAMBAR;LAN, TAO;PHILBIN, VICTORIA JANE;AGRAWAL, SUDHIR |
分类号 |
C12N15/117;A61K31/7105;A61K39/39;A61P37/02;A61P37/04;C07H21/00;C07H21/02 |
主分类号 |
C12N15/117 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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