| 发明名称 | Crystal of 6,7-unsaturated-7-carbamoyl morphinan derivative and method for producing the same | ||
| 摘要 | Stable crystalline forms of a compound represented by the formula (IA):; an acid addition salt, and/or a solvate thereof are provided by the present invention. Said crystalline forms are extremely useful as materials for preparing medicines. Novel processes for preparing 6,7-unsaturated-7-carbamoyl morphinan derivatives are also provided by the present invention. | ||
| 申请公布号 | US9108975(B2) | 申请公布日期 | 2015.08.18 |
| 申请号 | US201113884770 | 申请日期 | 2011.11.11 |
| 申请人 | Shionogi & Co., LTD. | 发明人 | Tamura Yoshinori;Noguchi Kouichi;Inagaki Masanao;Morimoto Kenji;Haga Nobuhiro;Oda Shinichi;Omura Sohei |
| 分类号 | C07D471/00;A61K31/44;C07D489/08;C07C51/41;C07C53/10;C07C303/32;C07C309/30;C07D271/06;A61K9/16 | 主分类号 | C07D471/00 |
| 代理机构 | Finnegan, Henderson, Farabow, Garrett & Dunner LLP | 代理人 | Finnegan, Henderson, Farabow, Garrett & Dunner LLP |
| 主权项 | 1. A p-toluenesulfonic acid salt of a compound of the formula (IA): | ||
| 地址 | Osaka JP | ||