发明名称 | Reagents and methods for cancer treatment and prevention | ||
摘要 | The invention generally relates to the prevention and/or treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or standard chemotherapeutic agents. In one embodiment, the invention involves a method comprising: a) providing a subject with tumor cells, b) removing at least a portion of said tumor cells from said subject to create removed cells, c) treating at least a portion of said removed cells ex vivo, using stimulating agents, including thapsigargin and/or thapsigargin-related compounds, so as to create treated tumor cells; and d) introducing said treated tumor cells (or fragments thereof) in vivo into the same subject to generate anticancer therapeutic effects. | ||
申请公布号 | US9107863(B2) | 申请公布日期 | 2015.08.18 |
申请号 | US200611389695 | 申请日期 | 2006.03.27 |
申请人 | The Buck Institute For Age Reasearch | 发明人 | Niazi Kayvan R.;Rabizadeh Shahrooz;Bredesen Dale E. |
分类号 | A61K39/00;A61K31/365 | 主分类号 | A61K39/00 |
代理机构 | Fish & Tsang, LLP | 代理人 | Fish & Tsang, LLP |
主权项 | 1. A method for treating a patient with skin cancer comprising: a) removing skin cancer cells from said patient, b) exposing at least a portion of said removed cells ex vivo to an agent selected from the group consisting of thapsigargin and thapsigargicin, c) lysing said treated cancer cells, and d) introducing said lysed cancer cells in vivo into said patient to generate an anticancer therapeutic effect. | ||
地址 | Novato CA US |