Fluid delivery catheter with pressure-actuating needle deployment and retraction

摘要

A fluid delivery catheter that uses micro-needles for fluid delivery though a vessel wall. The catheter may provide fluid delivery therapy for various procedures, such as, for example, delivery of tumescent fluid or renal denervation. The catheter includes an elongate member with deployable and retractable needles disposed about a distal end of the elongate member. The needles may be disposed radially about the distal end and/or along a length of the distal end.

主权项

1. An apparatus for delivery of a fluid at a treatment site, the apparatus comprising:
an elongate catheter; a non-pressure-expandable outer sleeve defining a treatment length at or near a distal end of the catheter, the outer sleeve defining a plurality of spaced apertures and an outer sleeve lumen; a flexible inner lining disposed within the outer sleeve lumen and defining a plurality of independently pressure-deformable portions and a lining lumen, wherein each of the plurality of pressure deformable portions is biased radially inward and is generally aligned with one of the plurality of spaced apertures; a plurality of micro-needles secured to the pressure-deformable portions and in fluid communication with the lining lumen, wherein the pressure-deformable portions and the micro-needles are recessed beneath an outer surface of the outer sleeve in an at-rest configuration, and the pressure-deformable portions are deformable to an extended position in which at least a portion of the micro-needles protrude above the outer surface of the outer sleeve, and a flexible wire configured to engage with the deformable portions as the flexible wire is axially advanced into the lining lumen so as to move at least one of the deformable portions from the at-rest configuration to the extended position, the flexible wire being further configured to allow passage of a fluid through the lining lumen and into the deformable portions when the flexible wire is advanced into the lining lumen.