Chewable enteric coated aspirin tablets

摘要

The invention relates to a tablet capable of being chewed or disintegrated in the oral cavity, which comprises an enteric coated aspirin active ingredient, and preferably a lightly compressed matrix comprising directly compressible carbohydrate(s) and at least one sweetener.

主权项

1. A process for preparing a chewable tablet comprising applying an enteric coating onto aspirin particles, wherein said enteric coating is formed from a dispersion of triethyl citrate and an anionic copolymer of methacrylic acid and methacrylates, and compressing said enteric-coated aspirin particles into tablet form, wherein said aspirin particles are not granulated during processing, and wherein said aspirin particles comprise a matrix comprising (a) about 75% to about 90% by weight of dextrose monohydrate, and (b) about 0.05% to about 2.0% saccharin.