Ventricular pacing to augment atrial natriuretic hormone production

摘要

Intermittent delivery of ventricular pacing pulses synchronized to occur during an atrial diastole time period can be used to provide atrial stretch therapy and augment the production and release of atrial natriuretic hormone.

主权项

1. An apparatus comprising:
a cardiac rhythm management device comprising:
a ventricular pacing circuit, configured to deliver a ventricular pace; anda processor circuit, coupled to the ventricular pacing circuit, the processor configured to comprise a first operating mode, the processor configured to time delivery of the ventricular pace, when in the first operating mode, so that:delivery of the ventricular pace is synchronized to occur during an atrial diastole time period;delivery of the ventricular pace results in a substantial overlap of ventricular systole and atrial systole; anda paced ventricular contraction is substantially concurrent with a paced or sensed atrial contraction during the same cardiac cycle.