发明名称 Modulators of <i>Candida </i>hyphal morphogenesis and uses thereof
摘要 The invention relates to modulation of fungal morphology between yeast-to-hyphal growth transition by controlling muramyl-L-alanine concentration and uses thereof.
申请公布号 US9107905(B2) 申请公布日期 2015.08.18
申请号 US201313747413 申请日期 2013.01.22
申请人 Agency for Science, Technology and Research 发明人 Wang Yue;Xu Xiao-Li;Lee Raymond Teck Ho
分类号 C07K16/44;C12Q1/02;A61K39/395 主分类号 C07K16/44
代理机构 Wolf, Greenfield & Sacks, P.C. 代理人 Wolf, Greenfield & Sacks, P.C.
主权项 1. A method of determining the extent of Candida hyphal growth in a body fluid sample obtained from a patient having a Candida infection, comprising the step of measuring the amount of muramyl-L-alanine and/or compounds that include muramyl-L-alanine in their core structure in the body fluid sample.
地址 Singapore SG