发明名称 |
Modulators of <i>Candida </i>hyphal morphogenesis and uses thereof |
摘要 |
The invention relates to modulation of fungal morphology between yeast-to-hyphal growth transition by controlling muramyl-L-alanine concentration and uses thereof. |
申请公布号 |
US9107905(B2) |
申请公布日期 |
2015.08.18 |
申请号 |
US201313747413 |
申请日期 |
2013.01.22 |
申请人 |
Agency for Science, Technology and Research |
发明人 |
Wang Yue;Xu Xiao-Li;Lee Raymond Teck Ho |
分类号 |
C07K16/44;C12Q1/02;A61K39/395 |
主分类号 |
C07K16/44 |
代理机构 |
Wolf, Greenfield & Sacks, P.C. |
代理人 |
Wolf, Greenfield & Sacks, P.C. |
主权项 |
1. A method of determining the extent of Candida hyphal growth in a body fluid sample obtained from a patient having a Candida infection, comprising the step of measuring the amount of muramyl-L-alanine and/or compounds that include muramyl-L-alanine in their core structure in the body fluid sample. |
地址 |
Singapore SG |