发明名称 |
método de diagnóstico in vitro de um vírus hiv-1 não-m, não-o, e, método de seleção e tipagem de um vírus hiv-1 não-m, não-o |
摘要 |
<p>Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBE30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the following characteristics: little or no serological reactivity with regard to the proteins of the M and O groups and strong serological reactivity with regard to the proteins which are derived from the strain YBF30 according to the invention or the strain CPZGAB SIV; absence of genomic amplification when using primers from the env and gag regions of the M and O HIV-1 groups; genomic amplification in the presence of primers which are derived from the YBF30 strain according to the invention; and homology of the products of the envelope gene which is greater than 70% with regard to the YBF30 strain.</p> |
申请公布号 |
BRPI9713891(B1) |
申请公布日期 |
2015.08.18 |
申请号 |
BR19979713891 |
申请日期 |
1997.12.08 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE-INSERM;ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS;INSTITUT PASTEUR E IMMUNOLOGIA |
发明人 |
PHILIPPE MAUCLERE;IBTISSAM LOUSSERT-AJAKA;FRANÇOIS SARAGOSTI;SENTOB SARGOSTI;FRANÇOISE BARRE-SINOUSSI |
分类号 |
C12N15/49;A61K39/00;C07K14/16;C07K16/08;C12N7/00;C12N15/09;C12P21/02;C12P21/08;C12Q1/68;G01N33/569 |
主分类号 |
C12N15/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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