Compositions and methods for treatment or prevention of <i>Staphylococcus aureus </i>infections and for the eradication or reduction of <i>Staphylococcus aureus </i>on surfaces

摘要

Compositions and methods for treating or preventing S. aureus infections are provided. The compositions can be formulated as pharmaceutical compositions or as disinfectants, sanitizers, detergents or antiseptics, and can be used to eradicate or reduce S. aureus populations and thereby treat or prevent infection by S. aureus. The compositions include one or more digestive enzymes, e.g., one or more protease, lipases, and amylases. Methods of use of the compositions are also provided.

主权项

1. A method for the treatment or prevention of Staphylococcus aureus infection in a bird or a mammal, comprising administering to the bird or mammal a therapeutically effective amount of an oral pharmaceutical composition comprising digestive enzymes and a pharmaceutically acceptable excipient, wherein the digestive enzymes comprise a protease, an amylase, and a lipase, wherein the pharmaceutical composition is bacteriocidal or bacteriostatic for Staphylococcus aureus, wherein the pharmaceutical composition is formulated for oral administration, and wherein a ratio of total protease to total lipase ranges from about 1:1 to about 20:1.