| 发明名称 |
METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T. |
| 摘要 |
<p>The present invention comprises compounds of Formula (I), wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.</p> |
| 申请公布号 |
MX2015004783(A) |
申请公布日期 |
2015.08.14 |
| 申请号 |
MX20150004783 |
申请日期 |
2013.10.15 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
GOLDBERG, STEVEN;FOURIE, ANNE;WANG, AIHUA;EDWARDS, JAMES P.;BARBAY, KENT;VENKATESAN, HARIHARAN;WOLIN, RONALD L.;PIERCE, JOAN M.;LEONARD, KRISTI A.;KREUTTER, KEVIN D.;KUMMER, DAVID A.;MAHAROOF, UMAR;NISHIMURA, RACHEL;URBANSKI, MAUD;WOODS, CRAIG R.;XUE, XIAOHUA |
| 分类号 |
C07D401/14;A61K31/4709;A61P29/00;C07D401/06;C07D409/14;C07D413/14;C07D417/14 |
主分类号 |
C07D401/14 |
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