| 摘要 |
<p>This invention relates to an innovation of designing and using dental implant with apical pores for drug delivery to thebrain. Nano-drug is deposited beneath the nasal respiralpry mucosa or the maxillary sinus mucosa using a novel, cost effective, dental implant with; a porous apical end. The nanordrugdistributes into systemic circulation and to the bram from the delivery site using the neuralj lymphatic and the vascular route. The device provides long term, pain free, non-invasive, continuous and controlled drugdelivery to the brain.</p> |
