MICROORGANISM THAT DISPLAYS BIOTIN ON CELL SURFACE

摘要

It is an object of the present invention to provide a microorganism that can display, on the cell surface, any molecules other than a molecule comprising amino acids. The present invention provides a microorganism that displays biotin on a cell surface. The microorganism is capable of co-expressing a biotinylating enzyme and an acceptor peptide having a sequence recognized by the biotinylating enzyme, wherein the acceptor peptide is expressed on the cell surface, so that lysine of the acceptor peptide is biotinylated to display biotin on the cell surface. The present invention also provides a method for displaying an intended molecule, including not only a molecule comprising amino acids but also any molecules, on a cell surface of a microorganism.