METHOD FOR SEPARATION AND PURIFICATION OF PHOSPHATIDYLCHOLINE EMPLOYING MAGNETIC NANOPARTICLES AND COMPOSITIONS SO PRODUCED

摘要

A process for separation and purification of phosphatides, especially phosphatidylcholine, from vegetable lecithins, comprising deoiling with acetone, dissolved in alcoholic solvent and then treated with magnetic nanoparticles as sorbent, in order to adsorb non-choline phosphatides, and the purified phosphatidylcholine-rich composition derived therefrom.

主权项

1. A process for purifying phosphatidylcholine comprising:
mixing a plurality of magnetic nanoparticles coated with hydroxyapatite into a phosphatide mixture, said phosphatide mixture containing phosphatidylcholine and non-choline phosphatides, said hydroxyapatite on said magnetic nanoparticles adsorbing said non-choline phosphatides; applying a magnetic field to the resultant solution; and separating, after application of said magnetic field, the magnetic nanoparticles coated with hydroxyapatite with the adsorbed non-choline phosphatides from the resultant solution, whereby said process does not involve chromatographic solid phase extraction.