| 发明名称 |
RNAi INHIBITION OF α-ENaC EXPRESSION |
| 摘要 |
PROBLEM TO BE SOLVED: To provide effective therapies for treatment and prevention of diseases or disorders in which α-ENaC is implicated.SOLUTION: The invention relates to compositions and methods for modulating the expression of α-ENaC, and more particularly to the downregulation of α-ENaC expression by chemically modified oligonucleotides. |
| 申请公布号 |
JP2015145393(A) |
申请公布日期 |
2015.08.13 |
| 申请号 |
JP20150055783 |
申请日期 |
2015.03.19 |
| 申请人 |
ARROWHEAD RESEARCH CORP |
发明人 |
GINO VAN HEEKE;EMMA HICKMAN;DANAHAY HENRY LUKE;PAMELA TAN;ANKE GEICK;HANS-PETER VORNLOCHER |
| 分类号 |
A61K31/713;A61K48/00;A61P3/12;A61P9/12;A61P13/12;A61P43/00;C12N15/09;C12N15/113 |
主分类号 |
A61K31/713 |
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