摘要 |
Provided herein are methods of treating, preventing and/or managing locally advanced breast cancer, including inflammatory breast cancer, which comprise administering to a patient one or more immunomodulatory compounds or enantiomers or mixtures of enantiomers thereof, or pharmaceutically acceptable salts, solvates, hydrates, co-crystals, clathrates, or polymorphs thereof. |
主权项 |
1. A method of treating or managing locally advanced breast cancer comprising administering to a patient in need of such treatment or management a therapeutically effective amount of a compound selected from lenalidomide, pomalidomide, thalidomide, 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 3-(1-oxo-4-(4-(2-(pyrrolidin-1-yl)ethoxy)benzyloxy)isoindolin-2-yl)-piperidine-2,6-dione, 3-(4-(4-(2-morpholin-4-yl-ethoxy)-benzyloxy)-1-oxoisoindolin-2-yl)-piperidine-2,6-dione, 3-(4-(4-(2-morpholin-4-yl-ethyl)-benzyloxy)-1-oxo-1,3-dihydro-isoindol-2-yl}-piperidine-2,6-dione, or an enantiomer or mixture of enantiomers thereof; or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof. |