Compositions for the Transdermal Delivery of Physiologically Active Agents

摘要

The present invention is directed to compositions and processes for their use that allow for the delivery of physiologically active agents, using a unique composition containing glycerin and triglycerides in the proper ratio. The composition functions by acting both as a humectant and occlusive agent attracting water, returning the skin surface to a smooth state and holding water and physiologically active agents in place. The presence of both hydrophobic and hydrophilic components of the current invention solubilize the physiologically actives into the complex matrix, keeping the actives on the skin and allowing them to penetrate the skin over time, thus delivering the actives to the blood stream.

主权项

1. A composition that comprises:
(a) between 80 and 98% by weight of glycerin, and (b) between 1 and 15% by weight of a triglyceride having an iodine value of between 100 and 160 mg KOH/gm, and (c) between 1 and 5% by weight of a physiologically active agent.