Method and Apparatus for Ultrafast Multi-Wavelength Photothermal Optical Coherence Tomography (OCT)

摘要

Certain embodiments are directed to methods and apparatus for ultrafast MWP-OCT that is based on precise control of the OCT tunable-laser source combined with synchronization of the photothermal excitation laser emission. The invention is generally related to physics, biology, medicine, and imaging. In certain embodiments the field of the invention is directed to multiple wavelength photothermal optical coherence tomography.

主权项

1. A method for Fourier Domain optical coherence tomography comprising:
(a) exposing a first location of a target to a plurality of time resolved, narrow bandwidth optical coherence tomography (OCT) probe beams having a distinct fixed central frequency and an exposure time interval of at most 5 microseconds; (b) acquiring an interferometric signal related to each fixed central frequency OCT probe beam; (c) processing the acquired signals to produce an A-scan; and (d) repeating steps a-c to produce a plurality A-scans representative of the target.