摘要 |
In some aspects, the invention relates to methods of treating conditions associated with sleep disorders, comprising administering an agent that modulates the activity of a neuropeptide receptor or a neuropeptide receptor ligand. In some aspects, the invention relates to methods of screening agents that modulate the activity of a neuropeptide receptor in an organism, optionally using ceils or organisms comprising a genetic modification that affects a neuropeptide signaling pathway. In some aspects, the invention relates to methods of characterizing a condition associated with a sleep disorder comprising sequencing a nucleic acid encoding either a neuropeptide receptor or a neuropeptide receptor ligand and comparing the sequence with a reference sequence. |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY;CHOW, SUK, HEN;LEE, DANIEL, A.;PROBER, DAVID, A.;STERNBERG, PAUL, W. |
发明人 |
CHOW, SUK, HEN;LEE, DANIEL, A.;PROBER, DAVID, A.;STERNBERG, PAUL, W. |