发明名称 |
ORGANIC ACIDS AS GROWTH INHIBITORS OF PATHOLOGICAL CALCIFICATION AND USES THEREOF |
摘要 |
In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium oxalate crystal growth. In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium phosphate crystal growth. In some embodiments, such a composition comprises at least one citrate derivative of an organic acid and at least one pharmaceutically acceptable carrier. In another embodiment, the present disclosure relates to a method of controlling calcium oxalate crystal growth in a subject in need thereof. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. |
申请公布号 |
WO2015120272(A1) |
申请公布日期 |
2015.08.13 |
申请号 |
WO2015US14818 |
申请日期 |
2015.02.06 |
申请人 |
UNIVERSITY OF HOUSTON SYSTEM |
发明人 |
RIMER, JEFFREY, D.;ASPLIN, JOHN |
分类号 |
A61K31/194;A61K31/19;A61P13/12 |
主分类号 |
A61K31/194 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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