METHOD FOR CAPTURING TARGET SUBSTANCE, SOLID-PHASE CARRIER FOR CAPTURING TARGET SUBSTANCE, AND METHOD FOR PRODUCING SOLID-PHASE CARRIER

摘要

Provided are: a solid-phase carrier that has extremely low non-specific adsorption of biological substances such as proteins, peptides, nucleic acids and cells, and is capable of maintaining the activity of bound ligands at a high level; and a method for capturing a target substance using said solid-phase carrier.　The method for capturing a target substance is characterized by comprising: a step for preparing a solid-phase carrier for capturing a target substance, said carrier having a base material, at least a portion of the surface thereof being formed of or coated with saccharides, and having a linker of 5-100 atoms having a reactive functional group for binding ligands that specifically bind to the target substance, wherein the saccharides are chemically bound to the linker; a step for binding the ligands to the solid-phase carrier to obtain a solid-phase carrier having ligands bound thereto; and a step for bringing the solid-phase carrier having the ligands bound thereto into contact with a sample containing the target substance that specifically bind to the ligands.