摘要 |
This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies. |
申请人 |
MEDIMMUNE, LLC;ABBOTT LABORATORIES |
发明人 |
CHOWDHURY, PARTHA;VARKEY, REENA;LIANG, MEINA;LEE, YEN-WAH;STREICHER, KATIE;RANADE, KOUSTUBH;GRANT, ETHAN;GREENLEES, LYDIA;YAO, YIHONG;PARKER, MELISSA;DAVIS, GERARD;JEANBLANC, NICOLETTE;BROPHY, SUSAN;DILLE, BRUCE |