SPECIFIC EXPRESSION OF HALF-TRNA IN CANCERS

摘要

The present invention relates to systems, devices and methods for diagnosing cancer. In various embodiments, the present invention provides a method for quantifying a 5'-htRNA; a method for quantifying a 3'-htRNA; a method for obtaining a DNA library of 5'-htRNAs and a DNA library of 5'-htRNAs obtained therefrom; and a method for obtaining a DNA library of 3'-htRNAs and a DNA library of 3'-htRNAs obtained therefrom. The invention also teaches a method for determining the presence or absence of a cancer cell in a biological sample; a method of diagnosing cancer in a subject; and a method of prognosing cancer in a subject.