发明名称 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]octane- or heptane-nitrile as JAK inhibitors
摘要 The present invention relates to the Janus kinase (JAK) inhibitors 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)-1H-pyrazol-l-yl]octanenitrile or 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-y1)-1H- pyrazol-l-yl]heptanenitrile, as well as its compositions and methods of use, which is useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, skin disorders, cancer, and other diseases.
申请公布号 AU2010249443(B2) 申请公布日期 2015.08.13
申请号 AU20100249443 申请日期 2010.05.21
申请人 INCYTE HOLDINGS CORPORATION 发明人 LI, YUN-LONG;RODGERS, JAMES D.
分类号 C07D487/04;A61K31/519;A61P17/00;A61P27/02;A61P29/00;A61P35/00 主分类号 C07D487/04
代理机构 代理人
主权项
地址