发明名称 |
Oligomer-opioid agonist conjugates |
摘要 |
<p>The invention provides conjugates wherein the opioid agonists, hydroxycodone (oxycodone) and hydrocodone (dihydrocodeiπone) are covalently attached to poly(ethylene glycol) oligomers. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the opioid agonist not attached to the PEG oligomers.</p> |
申请公布号 |
AU2010276244(B2) |
申请公布日期 |
2015.08.13 |
申请号 |
AU20100276244 |
申请日期 |
2010.07.21 |
申请人 |
NEKTAR THERAPEUTICS |
发明人 |
RIGGS-SAUTHIER, JENNIFER;DENG, BO-LIANG;RILEY, TIMOTHY A. |
分类号 |
A61K47/48;A61P25/04;A61P25/36 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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