发明名称 PYRAZOLOPYRIMIDINE COMPOUNDS
摘要 Compounds of formula (I) and salts thereof:;;wherein R1 is n-C1-6alkyl or C1-2alkoxyC1-2alkyl-, R2 is halo, OH or C1-3alkyl, m is an integer having a value of 4, 5, 6 or 7, n is an integer having a value of 0, 1, 2 or 3, and p is an integer having a value of 0, 1 or 2, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
申请公布号 US2015225403(A1) 申请公布日期 2015.08.13
申请号 US201314423400 申请日期 2013.08.22
申请人 GlaxoSmithKline LLC 发明人 Coe Diane Mary;Smith Stephen Allan
分类号 C07D487/04;A61K39/00;A61K39/39 主分类号 C07D487/04
代理机构 代理人
主权项 1. A compound of formula (I), or a salt thereof:wherein: R1 is n-C3-6alkyl or C1-2alkoxyC1-2alkyl-; each R2 independently represents halo, OH or C1-3alkyl; m is an integer having a value of 4, 5, 6 or 7; n is an integer having a value of 0, 1, 2 or 3; p is an integer having a value of 0, 1 or 2.
地址 Wilmington DE US