| 发明名称 |
PROCESS FOR THE PURIFICATION OF FLUTICASONE PROPIONATE USING A KETONE SOLVENT AND WATER AS ANTI-SOLVENT |
| 摘要 |
<p>The present disclosure relates to an improved process for the purification of fluticasone propionate by: a) dissolving fluticasone propionate in a ketone solvent to produce a mixture, b) heating the mixture slowly for 1-2 hours to get a clear solution, c) adding water to the step (b) solution at 50-60°C, d) cooling to -5°C to 10°C, and e) isolating fluticasone propionate.</p> |
| 申请公布号 |
WO2015118474(A1) |
申请公布日期 |
2015.08.13 |
| 申请号 |
WO2015IB50871 |
申请日期 |
2015.02.05 |
| 申请人 |
MYLAN LABORATORIES LTD. |
发明人 |
JADHAV, SAKHARAM;BOHARA, CHANDERSINGH;WAGH, GHANSHYAM;GORE, VINAYAK GOVIND;GADAKAR, MAHESHKUMAR |
| 分类号 |
C07J31/00 |
主分类号 |
C07J31/00 |
| 代理机构 |
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