发明名称 |
APPROVAL PREDICTION DEVICE, APPROVAL PREDICTION METHOD, AND PROGRAM |
摘要 |
According to an aspect of the present invention, similarity centrality measures that are centrality measures of proteins that a protein similarity network includes are calculated, interaction centrality measures that are centrality measures of the proteins that the protein-protein interaction network includes are calculated, a rejection score that represents probability of a compound to be validated to be classified as a rejected drug is calculated using classifiers that use, as training data, the approval attributes of the respective drugs, the sum and average of the similarity centrality measures per target for each drug, and the sum and average of the interaction centrality measures per target for each drug, and the rejection score is output. |
申请公布号 |
EP2905363(A1) |
申请公布日期 |
2015.08.12 |
申请号 |
EP20130844515 |
申请日期 |
2013.09.27 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
DA SILVA LOPES, TIAGO JOSE;KITANO, HIROAKI;KAWAOKA, YOSHIHIRO |
分类号 |
G06F19/12;C40B30/02;G06F17/18;G06F17/30;G06F19/00;G06Q30/02 |
主分类号 |
G06F19/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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