| 发明名称 |
FIBROBLAST GROWTH FACTOR 21 VARIANTS |
| 摘要 |
<p>This present invention relates to pharmacologically potent and/or stable variants of human fibroblast growth factor 21 (FGF21), pharmaceutical compositions comprising FGF21 variants, and methods for treating type 2 diabetes, obesity, dyslipidemia, or metabolic syndrome, or any combination thereof, using such variants.</p> |
| 申请公布号 |
EP2763689(B1) |
申请公布日期 |
2015.08.12 |
| 申请号 |
EP20120766847 |
申请日期 |
2012.09.25 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
DICKINSON, CRAIG, DUANE;DRIVER, DAVID, ALBERT;DARLING, RYAN, JAMES;GONCIARZ, MALGORZATA, DONATA;MICANOVIC, RADMILA |
| 分类号 |
A61K38/00;A61K38/18;C07K14/50 |
主分类号 |
A61K38/00 |
| 代理机构 |
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