发明名称 |
合理的に設計された、非パリンドローム認識配列を有する単鎖メガヌクレアーゼ |
摘要 |
Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of enzyme subunits having specificity for different recognition sequence half-sites are joined into a single polypeptide to form a functional heterodimer with a non- palindromic recognition sequence. The invention also relates to methods of producing such meganucleases, and methods of producing recombinant nucleic acids and organisms using such meganucleases. |
申请公布号 |
JP5761996(B2) |
申请公布日期 |
2015.08.12 |
申请号 |
JP20100532293 |
申请日期 |
2008.10.31 |
申请人 |
プレシジョン バイオサイエンシズ,インク. |
发明人 |
スミス,ジェイムス,ジェファーソン;ジャンツ,デレック |
分类号 |
C12N9/16;A01H5/00;A01K67/027;C12N1/15;C12N1/19;C12N5/10;C12N15/09 |
主分类号 |
C12N9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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