发明名称 |
Cell permeable peptide |
摘要 |
<p>The present invention relates that peptides having an ability to bind to a cell or penetrate into a cell are selectively enriched from a random peptide library with a diversity of not less than one hundred millions of peptides using a phage surface display technique, and cytoplasmic transfer is evaluated by using protein synthesis inhibition as an indicator by adding into a cell, a fusion body of the selectively enriched peptide and a protein synthesis inhibitory factor (PSIF) that can not solely penetrate into the cell.</p> |
申请公布号 |
EP2177531(B1) |
申请公布日期 |
2015.08.12 |
申请号 |
EP20090009933 |
申请日期 |
2006.02.09 |
申请人 |
OSAKA UNIVERSITY;NITTO DENKO CORPORATION |
发明人 |
NAKAGAWA, SHINSAKU;MAYUMI, TADANORI;FUKUI, KIICHI |
分类号 |
C07K7/08;A61K9/06;A61K9/08;A61K9/70;A61K9/72;A61K39/00;A61K47/48;C07K14/16;C07K19/00;C12N15/09 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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