Transgenic microbial polyhydroxyalkanoate producers

摘要

The present invention provides a method of screening for a transgenic microbial cell with a high level of expression of a chromosomally integrated transgene that encodes a PHA biosynthetic enzyme, the method comprising
(a) randomly inserting a transgene that encodes a PHA biosynthetic enzyme into the chromosome of a microbial host cell; and
(b) determining the level of expression of the thus integrated transgene.