| 摘要 |
<p>A method of monitoring a breast cancer patient's response to treatment, or of detecting recurrence of breast cancer, the method comprising a step of assaying a plurality of samples obtained from the patient over a period of time for expression levels of a plurality of biomarkers including Cancer Antigen 15-3 (CA 15-3) and one of either Glutamate or 12-Hydroxyeicosatetraenoic acid (12-HETE), and detecting a change in expression levels of CA 15-3 and one (or both) of either Glutamate or 12-HETE over the time period, wherein detection of a decreased expression levels of CA 15-3 and one of either Glutamate or 12-HETE over the time period is indicative of a response to therapy and wherein detection of increased or stable expression levels of CA 15-3 and one of either Glutamate or 12-HETE over the time period is indicative of a non-response to breast cancer therapy.</p> |
