发明名称 |
METHOD AND PHARMACEUTICAL COMPOSITION FOR INHIBITING PI3K/AKT/MTOR SIGNAL PATH |
摘要 |
The present invention relates to a pharmaceutical composition of PRCP antagonist, PREP antagonist, or PRCP-PREP dual antagonist. The present invention also relates to a pharmaceutical composition jointly using PRCP antagonist and mTOR antagonist, or jointly using PREP antagonist and mTOR antagonist, or jointly using PRCP-PREP dual antagonist and mTOR antagonist. In addition, the present invention also relates to a method for utilizing the pharmaceutical compositions to treat and prevent cancers and diseases related to insulin receptor substrate protein and PI3K/AKT/mTOR signal pathway. |
申请公布号 |
EP2905032(A1) |
申请公布日期 |
2015.08.12 |
申请号 |
EP20130841191 |
申请日期 |
2013.09.29 |
申请人 |
TARGETED THERAPEUTICS, LLC |
发明人 |
DUAN, LEI;LEVENSON, VIKTOR;YING, GUOGUANG |
分类号 |
A61K45/06;A61K31/381;A61K31/4025;A61K31/436;A61K31/4436;A61K31/4439;A61K31/7052;A61K31/7105;A61P3/00;A61P21/00;A61P25/28;A61P35/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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