Crystals of salts of phenylalanine derivatives

摘要

Provided is a crystal of a salt of the compound represented by formula (I), which is excellent in its solubility in water. In particular, also provided is a crystal of hydrochloride, hydrobromate, sulfate, nitrate, p-toluenesulfonate or methanesulfonate of the compound represented by formula (I).;

主权项

1. A method of treating rheumatoid arthritis, inflammatory, intestinal diseases, systemic lupus erythematosus, disseminated or multiple sclerosis, Sjogren's syndromes, asthma, psoriasis, allergy, diabetes (mellitus), cardiovascular diseases, arterial sclerosis, restenosis, tumor hyperplasia, tumor metastasis, or graft rejection, comprising administering to a subject in need thereof an effective amount of a the compound represented by formula (I):
or a pharmaceutically-acceptable acid addition salt thereof, and at least one additional pharmaceutical agent selected from the group consisting of 5-ASA pharmaceutical preparations, adrenocortical hormone-containing pharmaceutical preparations, antibacterial agents, immunosuppressive agents and anti-cytokine agents.