| 发明名称 | Bispecific antisense oligonucleotides that inhibit IGFBP-2 and IGFBP-5 and methods of using same | ||
| 摘要 | Bispecific antisense oligonucleotides which consist essentially of a sequence of bases that is complementary to portions of both the gene encoding human IGFBP-2 and the gene encoding human IGFBP-5 are useful in as antisense therapeutics in the treatment of endocrine-regulated cancers. | ||
| 申请公布号 | US9101646(B2) | 申请公布日期 | 2015.08.11 |
| 申请号 | US201012752581 | 申请日期 | 2010.04.01 |
| 申请人 | The University of British Columbia | 发明人 | Gleave Martin;Signaevsky Maxim |
| 分类号 | C07H21/04;A61K31/713;C12N15/113;A61K38/00 | 主分类号 | C07H21/04 |
| 代理机构 | Larson & Anderson, LLC | 代理人 | Larson & Anderson, LLC |
| 主权项 | 1. A bispecific antisense oligodeoxynucleotide consisting of Seq. ID No. 5, wherein the oligodeoxynucleotide is modified to enhance in vivo stability. | ||
| 地址 | Vancouver CA | ||