发明名称 Use of Danshensu, Notoginsenoside R1 or their combination in preparation of medicaments for preventing and treating diseases caused by microcirculation disorder
摘要 The present invention relates to a new use of traditional Chinese drug products of Danshensu (DLA), Notoginsenoside R1 (R1) and their combination, in particular to the therapeutic and preventive effects of DLA, R1 and their combination on the diseases caused by microcirculation disorder.
申请公布号 US9101640(B2) 申请公布日期 2015.08.11
申请号 US201013505051 申请日期 2010.11.04
申请人 Tasly Pharmaceutical Group Co., Ltd. 发明人 Han Jingyan;Guo Jun;Yang Jiying;Sun Kai;Wang Mingxia;Zhang Yu;Liu Yuying
分类号 C07C59/52;C07H15/256;A61K31/704;A61K31/192 主分类号 C07C59/52
代理机构 Lando & Anastasi, LLP 代理人 Lando & Anastasi, LLP
主权项 1. A method for treating at least one disease caused by a microcirculation disorder resulting from ischemia-reperfusion in a subject, the method comprising administering an effective amount of a first medicine prepared from a first combination of Danshensu and Notoginsenoside R1 to the subject, the Danshensu having a weight ratio relative to the Notoginsenoside R1 in a range of about 1:4 to about 4:1, wherein the at least one disease caused by the microcirculation disorder resulting from ischemia-reperfusion is selected from the group consisting of: pollinosis, asthma, diarrhea, hypertension, infection, and traumatic injury.
地址 Tianjin CN