发明名称 |
METHOD FOR AMIDATING POLYPEPTIDES WITH BASIC AMINOACID C-TERMINALS BY MEANS OF SPECIFIC ENDOPROTEASES |
摘要 |
<p>The invention relates to a method for producing C-terminal amidated dibasic or polybasic peptides, consisting in reacting two peptides in the presence of trypsin biologically active enzymes and, if necessary, in purifying the thus obtainable compounds of formula (I) by means of protein chemistry.</p> |
申请公布号 |
CA2623547(C) |
申请公布日期 |
2015.08.11 |
申请号 |
CA20062623547 |
申请日期 |
2006.09.13 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
RISSOM, SEBASTIAN;HABERMANN, PAUL;SALAGNAD, CHRISTOPHE;ZOCHER, FRANK;LANDRIC-BURTAIN, LAURE |
分类号 |
C07K14/575;C07K14/605;C12P21/02;C12P21/06 |
主分类号 |
C07K14/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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