发明名称 Cyclosporin compositions
摘要 A composition is disclosed herein comprising from about 0.001% to about 0.4% cyclosporin A, castor oil, and a surfactant selected from the group consisting of alcohol ethoxylates, alcohols, alkyl glycosides, alkyl polyglycosides, alkylphenol ethoxylates, amine oxides, block polymers, carboxylated alcohol or alkylphenol ethoxylates, carboxylic acids/fatty acids, cellulose derivatives, ethoxylated alcohols, ethoxylated alkylphenols, ethoxylated aryl phenols, ethoxylated fatty acids, ethoxylated fatty acids, ethoxylated fatty esters and oils, fatty alcohols, fatty esters, glycol esters, lanolin-based derivatives, lecithin and lecithin derivatives, lignin and lignin derivatives, methyl esters, monoglycerides and derivatives, phosphalipids, polyacrylic acids, polyethylene glycols, polyethylene oxide-polypropylene oxide copolymers, polyethylene oxides, polymeric surfactants, polypropylene oxides, propoxylated alcohols, propoxylated alkyl phenols, propoxylated fatty acids, protein-based surfactants, sarcosine derivatives, silicone-based surfactants, sorbitan derivatives, stearates, sucrose and glucose esters and derivatives, and combinations thereof.
申请公布号 US9101574(B2) 申请公布日期 2015.08.11
申请号 US201314059025 申请日期 2013.10.21
申请人 Allergan, Inc. 发明人 Chang James N.;Olejnik Orest;Firestone Bruce A.
分类号 A61K38/13;A61K38/12;A61K9/36;A61K31/175;A61K9/00;A61K9/107 主分类号 A61K38/13
代理机构 代理人 Wine Laura L.;German Joel B.;Condino Debra D.
主权项 1. An ophthalmically acceptable emulsion comprising from about 0.001% to 0.4% cyclosporin A, castor oil, Polysorbate 80, Pemulen, and a cellulose derivative selected from the group consisting of hydroxypropylmethyl cellulose and carboxymethyl cellulose.
地址 Irvine CA US