Pharmaceutical composition comprising mannooligosaccharides derived from coffee for treatment of lifestyle-related disease, and food useful for treatment of lifestyle-related disease

摘要

A pharmaceutical composition for preventing or treating lifestyle-related disease is provided. Also provided is a food useful for the prevention or treatment of lifestyle-related disease. The pharmaceutical composition contains, as an active ingredient, a sugar in which a mannose unit makes up 66% or more in terms of the number of mannose units and which has a polymerization degree of 3 to 10.

主权项

1. A method for treating lifestyle-related diseases, wherein an effective dose of a pharmaceutical composition is administered to a patient who is at risk of contracting or is suffering from a lifestyle-related disease in an amount effective to reduce liver lipids and/or reduce absorption of sugar in the patient when compared to an individual that is not administered the pharmaceutical composition, the pharmaceutical composition including an effective amount of an active ingredient comprising a sugar with a degree of polymerization of 5-10 and mannose units constituting at least 66% of the numerical content, wherein less than about 1% of the sugar has a degree of polymerization of less than 3, wherein the lifestyle-related disease is selected from the group consisting of obesity, metabolic syndrome, hyperlipidemia, diabetes, hypercholesterolemia, and liver failure, wherein the sugar is obtained by performing hydrolysis treatment on mannan and the mannan is obtained from coffee beans and/or a coffee extract residue.