发明名称 Treatment of bone marrow edema (oedema) with polysulfated polysaccharides
摘要 A method for the treatment of bone marrow edema in a mammal comprising administering an effective amount of a polysulfated polysaccharide including salts thereof, to a mammal in need of such treatment.
申请公布号 US9101650(B2) 申请公布日期 2015.08.11
申请号 US201213983406 申请日期 2012.02.02
申请人 PARADIGM HEALTH SCIENCES PTY LTD 发明人 Ghosh Peter
分类号 A61K31/737;A61K31/727 主分类号 A61K31/737
代理机构 Thorpe North & Western LLP 代理人 Thorpe North & Western LLP
主权项 1. A method for the treatment of bone marrow edema in a mammal not suffering from osteoarthritis comprising administering from about 1 mg/kg to about 2 mg/kg per dose of a polysulfated polysaccharide selected from the group consisting of pentosan polysulfate, the sodium salt of pentosan polysulfate (NaPPS), the magnesium salt of pentosan polysulfate (MgPPS), and the calcium salt of pentosan polysulfate (CaPPS) to a mammal in need of such treatment once daily, thrice weekly, or twice weekly.
地址 Fairlight, New South Wales AU