发明名称 |
Treatment of bone marrow edema (oedema) with polysulfated polysaccharides |
摘要 |
A method for the treatment of bone marrow edema in a mammal comprising administering an effective amount of a polysulfated polysaccharide including salts thereof, to a mammal in need of such treatment. |
申请公布号 |
US9101650(B2) |
申请公布日期 |
2015.08.11 |
申请号 |
US201213983406 |
申请日期 |
2012.02.02 |
申请人 |
PARADIGM HEALTH SCIENCES PTY LTD |
发明人 |
Ghosh Peter |
分类号 |
A61K31/737;A61K31/727 |
主分类号 |
A61K31/737 |
代理机构 |
Thorpe North & Western LLP |
代理人 |
Thorpe North & Western LLP |
主权项 |
1. A method for the treatment of bone marrow edema in a mammal not suffering from osteoarthritis comprising administering from about 1 mg/kg to about 2 mg/kg per dose of a polysulfated polysaccharide selected from the group consisting of pentosan polysulfate, the sodium salt of pentosan polysulfate (NaPPS), the magnesium salt of pentosan polysulfate (MgPPS), and the calcium salt of pentosan polysulfate (CaPPS) to a mammal in need of such treatment once daily, thrice weekly, or twice weekly. |
地址 |
Fairlight, New South Wales AU |