| 发明名称 | Intranasal pharmaceutical compositions with improved pharmacokinetics | ||
| 摘要 | Methods are provided for the engineering of inhalable dry powder pharmaceutical formulations with desired pharmacokinetic profiles and parameters. Compositions with improved pharmacokinetics are disclosed. | ||
| 申请公布号 | US9101539(B2) | 申请公布日期 | 2015.08.11 |
| 申请号 | US201012780433 | 申请日期 | 2010.05.14 |
| 申请人 | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. | 发明人 | Nagata Ryoichi;Haruta Shunji |
| 分类号 | A61K9/14;A61K9/16;C07D209/10;A61K9/00 | 主分类号 | A61K9/14 |
| 代理机构 | Wilson, Sonsini, Goodrich & Rosati, PC | 代理人 | Wilson, Sonsini, Goodrich & Rosati, PC |
| 主权项 | 1. A composition comprising a therapeutic agent, wherein at least some of the therapeutic agent is present in a freebase form, and the therapeutic agent consists of two particle size distribution ranges, the first being less than 20 microns and the second being from about 38 microns to about 100 microns. | ||
| 地址 | Kagoshima JP | ||