发明名称 DIAGNOSTIC AND THERAPEUTIC METHODS
摘要 FIELD: medicine.SUBSTANCE: group of inventions relates to medicine and deals with a method of treating or preventing RHD, associated with GAS infection, which includes the introduction to a patient of at least one GAS antigen, selected from a group, including amino acid sequences SEQ ID NO: 1, 2, 3, 4, 5, 6, 7 or 8 or their functional equivalents. The group of inventions also deals with a method of diagnosing GAS-infection-associated RHD in the patient; a protein chip for the diagnostics of GAS-infection-associated RHD in the patient; a set, containing the said protein chip and instructions for application in the diagnostics of patients with the presence or with a risk of development of a rheumatic heart disease, associated with GAS infection.EFFECT: group of infections provides the treatment of GAS-infection-associated RHD; accurate RHD diagnostics.13 cl, 7 dwg, 1 tbl, 1 ex
申请公布号 RU2559584(C2) 申请公布日期 2015.08.10
申请号 RU20120120706 申请日期 2010.10.20
申请人 NOVARTIS AG 发明人 MARGARIT I ROS IMMAKULADA;VALERIO REGUTSTSI;AKHMED SOKHAIL;GRANDI GVIDO;BARTOLINI EHRIKA
分类号 A61K38/16;A61K39/09;A61P9/00;G01N33/569 主分类号 A61K38/16
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