ANTIBACTERIAL PHARMACEUTICAL COMPOSITION

摘要

The invention relates to the field of veterinary science and medicine and can be used for the prophylaxis and treatment of bacterial infections. The aim of the present invention is to design a preparation based on azithromycin in the form of a solution having a wide spectrum of antimicrobial activity and in the form of an injection solution ready for use not only for introduction intravenously but also for intramuscular subcutaneous intrauterine and intracisternal introduction. The antibacterial pharmaceutical composition comprises azithromycin solvents and/or cosolvents a preservative and an antioxidant. The antioxidant is in the form of ascorbic acid or sodium ascorbate or calcium ascorbate or palmitoyl ascorbate or 4 methyl 2 6 di tert butylphenol or tert butylhydroquinone 2 4 5 trihydroxy butyrophenone or sodium metabisulfite or alpha tocopherol or thioglycerine or combinations thereof whereas the preservative is in the form of benzyl alcohol parabens chloretone or combinations thereof with the following ratios of components by percentage mass: 5 50% azithromycin 0.1 0.2% antioxidant 1 2% preservative the remainder being solvents.