| 摘要 |
<p>The invention relates to 3D cell culture substrates comprising polymer brushes, wherein the polymer brushes comprise poly(N-isopropylacrylamide) polymers, the use of such substrates for the culture of 3D cell spheroids, and a method for culturing 3D cell spheroid. It further relates to a 3D cell spheroid, in particular comprising human cells, obtainable by the inventive 3D cell culture, the spheroid preferably not containing any scaffold or gel-matrix material, and a 3D culture system comprising the substrate according to the invention.</p> |
