| 发明名称 |
GENETIC TEST AND GENETIC BASIS FOR SCID IN PIGS |
| 摘要 |
The genetic basis for severe combined immunodeficiency disease (SCID) in pigs is described. In addition, tests for detecting pigs that are carriers for SCID or pigs with SCID are also described. Further, methods for producing pigs or herds of pigs with SCID are also described. Further, methods and compositions for treating, ameilioraing, inhibiting or correcting SCID are provided. |
| 申请公布号 |
US2015216147(A1) |
申请公布日期 |
2015.08.06 |
| 申请号 |
US201514592586 |
申请日期 |
2015.01.08 |
| 申请人 |
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. |
发明人 |
Dekkers Jack C.M.;Tuggle Christopher K.;Waide Emily H.;Ross Jason W.;Ellinwood N. Matthew;Schroyen Martine |
| 分类号 |
A01K67/027;C12N9/22;A61K49/00;C12N15/01;C12Q1/68 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A porcine subject with severe combined immunodeficiency disease (SCID) comprising a non-natually occurring nucleotide sequence having one or more of an insertion, a deletion, an inversion, or a single nucleotide polymorphism compared to a wild-type Artemis gene. |
| 地址 |
AMES IA US |
