发明名称 |
SUPERPARAMAGNETIC NANOPARTICLES AS A CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING (MRI) OF MAGNETIC SUSCEPTIBILITY (T2*) |
摘要 |
The invention relates to the use of biocompatible superparamagnetic nanoparticles comprising an inorganic core and a coating including an electrically charged polymer, and having low tissue and vascular adhesion, for use as contrast agents in magnetic resonance imaging (MRI). The aforementioned nanoparticles have novel pharmacokinetic and relaxability T2* properties, with high potential for use in in vivo tissue imaging and tumour perfusion strategies based on parameter T2*. |
申请公布号 |
US2015217003(A1) |
申请公布日期 |
2015.08.06 |
申请号 |
US201214374185 |
申请日期 |
2012.01.27 |
申请人 |
Garcia-Esteller Sebastián Cerdan;Hernández Daniel Calle;Egea Fernando Moreno |
发明人 |
Garcia-Esteller Sebastián Cerdan;Hernández Daniel Calle;Egea Fernando Moreno |
分类号 |
A61K49/18;A61K49/06 |
主分类号 |
A61K49/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Madrid ES |