发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION |
摘要 |
The potency of a series of Hexamethylene bis-acetamide (HMBA) derivatives of formula I, that induce Hexamethylene bis-acetamide inducible protein 1 (HEXIM1 ) was determined in cancer cells. The method of inducing HEXIM1 expression and cell differentiation in cancer and HIV cells are disclosed. Optimization of HMBA analogs that are symmetrical and unsymmetrical are also discussed. |
申请公布号 |
WO2015116968(A1) |
申请公布日期 |
2015.08.06 |
申请号 |
WO2015US13844 |
申请日期 |
2015.01.30 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY |
发明人 |
SU, BIN;MONTANO, MONICA M. |
分类号 |
A61K31/16;C07C233/05 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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