| 摘要 |
PROBLEM TO BE SOLVED: To provide RNA complexes with one or more hydroxymethyl substituted monomers incorporated into an RNA strand to be used in relation to RNA-guided gene regulation or gene analysis, in particular RNA interference (RNAi).SOLUTION: The present invention relates to an oligomer comprising one or more 2'-3'-seco-RNA monomer, and the oligomer comprising an RNA double-stranded part with first and second RNA strands, wherein the 2'-3'-seco-RNA monomer is expressed by the following formula monomer D, and at least ona part of the oligomer comprises a target sequence and a complementary sequence. [Base is nucleic acid base] |
